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Multidimensional Support for Cardiovascular Health
Maintains Healthy Cholesterol Levels
Helps Maintain Healthy Blood Sugar Balance
Supports Normal Blood Pressure
Description

CLINICAL  APPLICATIONS

 

 

  • Multidimensional Support for Cardiovascular Health
  • Maintains Healthy Cholesterol Levels
  • Helps Maintain Healthy Blood Sugar Balance
  • Supports Normal Blood Pressure

This product, a formula backed by extensive clinical research, is designed to address several factors for optimal cardiometabolic health. The powerful combination of berberine and MegaNatural® BP (a premium grape seed extract) address healthy heart function, healthy blood pressure, as well as healthy lipid and glucose levels. The far reaching effects of this product provide a comprehensive formula for those seeking to optimize their cardiovascular and metabolic health.

 

This product, a formula backed by extensive clinical research, is designed to address several factors for optimal cardiometabolic health. The powerful combination of berberine and MegaNatural® BP (a premium grape seed extract) address healthy heart function, healthy blood pressure, as well as healthy lipid and glucose levels. The far reaching effects of this product provide a comprehensive formula for those seeking to optimize their cardiovascular and metabolic health.

Overview

Clinical research is showing that cardiovascular health

strategies should address multiple metabolic factors in order to achieve optimal wellness. In addition to maintaining healthy lipid levels, cardiovascular wellness is also driven by many metabolic factors including blood sugar control, blood pressure, inflammatory balance and the profile of lipoproteins synthesized by the liver. This product offers multidimensional support for cardiovascular and metabolic health. Among their numerous benefits, berberine and MegaNatural® BP grape seed extract activate genes that regulate lipid and glucose utilization, support healthy liver function, and aid in

maintaining insulin sensitivity.

Berberine†

Berberine is a plant extract that has been used in Chinese and Aryuvedic medicine for over 2,500 years for its broad range of health-promoting properties. Berberine can be found in the roots and stems of plants such as Hydastatis canadensis

(goldenseal),  Coptis chinensis (goldenthread),  Berberis

aquifolium (Oregon grape), and Berberis vulgaris (barberry).

Clinical trials have demonstrated that berberine

administration supports cardiovascular health in a number

of synergistic ways including maintaining healthy blood

pressure, supporting healthy heart contraction and rhythm,

and supporting healthy cholesterol levels. [1,2] A clinical trial with 32 subjects demonstrated that administration of 500 mg of berberine given twice daily for three months helped maintain healthy LDL cholesterol and triglyceride levels, versus the control group. [3] Another recent study using 500 mg of berberine was able to reproduce similar results, confirming berberine’s powerful effect on specific cardiovascular markers including LDL cholesterol, HDL cholesterol and

triglyceride levels. [4]

In addition to maintaining healthy lipid levels, berberine has also been shown to maintain healthy blood glucose levels and support healthy liver function.[5]  The mechanism behind

berberine’s glucose balancing mechanisms include activation of a protein called adenosine mono-phosphate kinase (AMPK). AMPK coordinates both long-term and short-term metabolic changes, leading to an improvement in energy production and a reduction of energy storage. AMPK improves insulin sensitivity, and down-regulates genes involved in fat storage while activating genes involved with burning fat. [6]

Berberine has also been shown to promote the uptake of glucose through a mechanism that does not require insulin, promoting better glucose usage within the cell. [6] A study examining berberine’s metabolic supporting effects found that berberine improved glucose tolerance and maintained healthy insulin levels, while helping to maintain healthy total cholesterol and triglyceride levels after four weeks of

berberine administration. [7]

MegaNatural® BP Grape Seed Extract†

MegaNatural® BP is a premium grape seed extract backed by science. It is made in California from a special seed

blend extracted with water from a variety of white wine grape seeds. Grapes and grape products contain phenolic compounds which have been found to have health-

promoting properties, particularly because of their

involvement with the “French Paradox”, which is the high rate of cardiovascular wellness in the French population

despite their high intake of dietary fat. Phenolic compounds are found in high concentrations in grape seed extract and have been found to support healthy arterial dilation and blood flow. [8] Polyphenols have been shown to activate nitric oxide (NO) synthase. [9] NO synthases are a family of enzymes that increase the production of nitric oxide, a compound that promotes healthy blood vessel dilation and circulation throughout the body.

A study examining the effects of MegaNatural® BP grape seed extract in 27 volunteers found that after four weeks of supplementation with either 150mg or 300mg, the

participants were able to maintain healthy blood pressure levels. [10] The participants taking 300 mg also had a significant reduction in oxidized low-density lipoprotein when

compared to placebo.

Directions

3 capsules per day, or as recommended by your health care professional.

Does Not Contain

Does not contain gluten, corn, yeast, animal or dairy

products, artificial colors, artificial flavors, or preservatives.

Cautions

If you are pregnant or nursing, consult your health care professional before taking this product.

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